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A qualitative study that conducted semi-structured individual interviews with 44 cigarette smokers and Electronic Nicotine Delivery Systems (ENDS) users in the United States found that increased tobacco use was predominant and driven mainly by individual-level factors (i.e

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Overdose Risk and Emergency Warning Signs Overdose risk correlates primarily with CNS depressant properties, dosing variability in the illicit drug supply, and individual tolerance fluctuation following even brief abstinence

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